The episode begins with Chloe examining bacteria, while the bears are having fun in the lake. Chloe warns them about becoming ill and points to a sign saying "Prohibido Nadar" (Do not swim, in Spanish). They ignore it, saying bears don't get sick. They race over to Chloe and they when they get out they start getting sick. 30 minutes later Chloe brings them home and tires to get them in bed and tries making some soup. Grizz gets out trying to workout,which she stops him. She finds panda looking at possible diseases and he does a post saying he is going to die and then she takes his phone away. She tries to help Ice Bear but Grizzly comes back out and gets rid of most of the soup and drinks a sample of the lake water and Chloe brings him back to his room. She finds panda writing in his journal writing about stuff he leaves behind. She finds Grizz out and laying on a table with plates.Ice comes out pretty cold. All the bears start freaking out and Chloe finally snaps and makes them eat soup and watch TV. Chloe washes her hands and finds them worse then before and calls the doctor which she says they will be fine.
Meanwhile, Panda's post gets out to the government which they send a team to quarantine the bears. Chloe is told to stay away. The Hazmat Response Unit quarantines the whole cave. Chloe steals a suit and sneaks in. She finds the bears hooked up to machines. She uses her bugs to get rid of the unit. She puts them on a cart under a cover. The unit go back in and find the bears gone. A branch takes the cover off and the unit go after them. Chloe makes it to the doctor. The unit arrive and demand the doctor give them to her, but the doctor says they are fine and they believe her just because she is a doctor. Chloe ends up sick herself, to which the doctor says she should call her parents.
- Though there are several scenes of Dr. Decker's office, instead of Dr. Decker being present, a Dr. Sun helps the Bears and Chloe through receiving a proper diagnosis.
- Chloe reveals that she is, in fact, 10 years old.